Here is our story:
My wife and I used Clomid to help conceive. My wife just turned 35 in October and I am 29. We had a miscarriage in January and a host of other health issues throughout the year but we were finally able to conceive during the second week of October.
Everything was going smoothly until about week 5. We received a message at home (on our wedding anniversary!) that the hcg level dropped from about 4,000 taken on a Friday to something like 832 when measured on the following Monday. After a sleepless night, we go in to the doctor's office the next morning and they realize that the lab made a mistake and inserted a decimal in the number they gave over the phone, so instead of 832 it was really 8320. So that's one bullet dodged! All the ultrasounds and tests to this point were normal.
Week 7 we go to the high risk OB and a vaginal ultrasound is being performed. The technician is telling us everything looks great, the heart is beating over 140bpm, baby measures 11mm, etc. We're getting ready to leave when the doctor walks in and tells us that the yolk sac looks too big and to come back the following week for another ultrasound. I almost felt as if we were being sent away without an explanation of what's going on. Little did he know I'm the most annoying and involved patient on earth. I asked him what it meant and he said the large yolk sac is a sign that usually points to a pending miscarriage. We weren't told the size of the yolk sac or any other details.
We get home and immediately start searching the internet and find that an enlarged yolk sac is a sign of chromosomal abnormality or pending miscarriage. It was heart breaking. We went back for another ultrasound the following week and were told the yolk sac hadn't grown, that it measured 8.2mm but the baby was still growing on schedule at 17mm and a heartrate of 176bpm. A week later we go for yet another ultrasound and now the yolk sac has shrunk to 5.4mm baby still growing on schedule and heartrate looks good.
We scheduled a CVS for Week 11. We h ad to go for genetic counseling first and when I asked the counselor how many other women have walked in w/ an enlarged yolk sac, she replied that we were the first, which I found a bit odd. We went for the CVS on December 14th and it actually had to be performed TWICE because the doctor didn't get a sufficient sample the first time around. It was quite painful and uncomfortable for my wife. The doctor measured the yolk sac again and he said it was 9.1mm so it had grown! We were told to wait two weeks for the results but in some instances it can come back as soon as a week.
On December 23rd we finally got a phone call with the CVS results and we were told all the chromosomes are normal! Such a huge relief and a great Christmas present. We were finally able to announce the pregnancy to our families on Christmas Eve.
We go back to the OB next week and hopefully everything progresses smoothly from this point out. I hope the yolk sac is gone at this point. All the research is so negative on this point but hopefully we, too, can buck the trend.